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NANOMEDICINE
A Systems Engineering Approach


CONTENTS

FRONT MATTER
i
Nanomedicine: Dynamic Integration of Nanotechnology with Biomedical Science
Ki-Bum Lee, Aniruddh Solanki, John D. Kim and Jongjin Jung
1
Fundamental Mathematical Modeling Techniques for Nano Bio-Systems
Sharon Bewick, Mingjun Zhang and William R. Hamel
39
A Mathematical Formulation of the Central Dogma of Molecular Biology
Rui Gao, Juanyi Yu, Mingjun Zhang, Tzyh-Jong Tarn and Jr-Shin Li
81
System Approach to Characterize Living Drosophila Embryos for Biomedical Investigations
Yantao Shen and Ning Xi
117
Learning Signaling Pathway Structures
Karen Sachs and Solomon Itani
143
Computational Modeling of Tumor Biobarriers: Implications for Delivery of Nano-Based Therapeutics
Hermann B. Frieboes, Paolo Decuzzi, John P. Sinek, Mauro Ferrari and Vittorio Cristini
201
Multiscale-Multiparadigm Modeling and Simulation of Nanometer Scale Systems and Processes for Nanomedical Applications
Andres Jaramillo-Botero, Ravinder Abrol, Adri van Duin and William A. Goddard, III
245
Game Theoretical Formulation of the Immune System and Inspiration for Controlled Drug Delivery Application
Sharon Bewick, Mingjun Zhang and William R. Hamel
301
BACK MATTER
335
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